Understanding MCAS and Nutritional Support
Mast Cell Activation Syndrome (MCAS) is a condition involving inappropriate mast cell activation and the release of chemical mediators such as histamine, prostaglandins, leukotrienes, and tryptase. Diagnosis and treatment of MCAS should be directed by a qualified healthcare professional.
People researching MCAS frequently ask about dietary supplements and nutritional ingredients that may support normal mast cell function and healthy histamine metabolism. Supplements are not a substitute for medical evaluation or treatment of MCAS, but several naturally occurring compounds have been studied for their effects on mast cells, histamine, and inflammatory signaling.
Quercetin
Quercetin is a naturally occurring flavonoid found in many fruits and vegetables. Laboratory and preclinical research has investigated quercetin for its effects on mast cell activation and mediator release.
Because conventional quercetin has relatively limited absorption, some supplements use specialized formulations such as quercetin phytosome to improve bioavailability.
Luteolin
Luteolin is another naturally occurring flavonoid that has been studied for its effects on mast cell signaling and inflammatory pathways. It is frequently discussed alongside quercetin in research involving mast cells.
Vitamin C
Vitamin C is an essential nutrient with antioxidant activity and contributes to normal immune function. It has also been studied in relation to histamine metabolism and is commonly included in nutritional formulations designed to support individuals interested in maintaining healthy histamine balance.
Bromelain
Bromelain is a group of enzymes derived from pineapple. It has been studied for a variety of biological effects and is often combined with flavonoids such as quercetin in dietary supplements.
Choosing a Mast Cell Support Supplement
When evaluating supplements for mast cell and histamine support, consider the specific ingredients, their amounts, formulation and bioavailability rather than relying only on the name of the product.
MASTCORE® by AllerCore Health is a physician-formulated dietary supplement containing quercetin phytosome, luteolin, buffered vitamin C, and bromelain. It is formulated to support healthy mast cell function, histamine metabolism, and immune balance.*
MASTCORE® is a dietary supplement and is not intended to diagnose, treat, cure, or prevent MCAS or any other disease.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.